IKAP Antibody |
2337-002mg |
ProSci |
0.02 mg |
EUR 206.18 |
|
Description: IKAP Antibody: IKAP was initially identified as a scaffold protein of the IκB kinase complex that could bind to IKKα, IKKβ, NF-κB, and the NF-κB-inducing kinase (NIK), although later evidence has cast doubt on this. More recent reports show that mutations in IKAP such as a frameshift leading to a truncated protein or a missense mutation that leads to defective phosphorylation are responsible for the autosomal recessive genetic disease familial dysautonomia (FD). Reports indicating that it forms part of the RNA polymerase II transcription elongation complex suggest that this disease may be due to compromised transcription elongation. More recently, it was shown that IKAP associates with c-Jun N-terminal kinase (JNK) and could specifically enhance JNK activation induced by the upstream JNK activators MEKK1 and ASK1, indicating another possible cause for FD. |
Human Antibody Laboratories manufactures the antibodies to human ikap reagents distributed by Genprice. The Antibodies To Human Ikap reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact human Antibody. Other Antibodies products are available in stock. Specificity: Antibodies Category: To Group: Human Ikap
Human Ikap information
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MBS006887-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
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Human blocking antibodies (BA) ELISA Kit |
MBS263445-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 285 |
Human blocking antibodies (BA) ELISA Kit |
MBS263445-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 1670 |
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MBS263445-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 405 |
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Sunlong |
96 wells |
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|
Description: Sandwich ELISA |
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