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Apoptosis

A form of programmed cell death that occurs in multicellular organisms

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Month: December 2020

Transmissible cancers and the evolution of sex under the Red Queen hypothesis

December 10, 2020 at 5:24 pm | Antibodies, Assay Kits, Biology Cells, Clia Kits, Culture Cells, Devices, DNA, DNA Templates, Elisa Kits, Enzymes, Equipments, Exosomes, Gels, Isotypes, Medium & Serums, Panel, Particles, PCR, Pcr Kits, Peptides, Recombinant Proteins, Ria Kits, RNA, Test Kits, Vector & Virus, Western Blot | Jonathan -

The predominance of sexual copy in eukaryotes stays paradoxical in evolutionary idea. Of the hypotheses proposed to resolve this paradox, the ‘Pink Queen speculation’ emphasises the potential of antagonistic interactions to trigger fluctuating choice, which favours the evolution and upkeep of intercourse. Whereas empirical and theoretical developments have targeted on host-parasite interactions, the premises of

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“Transmissible cancers and the evolution of sex under the Red Queen hypothesis”

Wnt/β-Catenin Target Genes in Colon Cancer Metastasis: The Special Case of L1CAM

at 5:24 pm | Antibodies, Assay Kits, Biology Cells, Clia Kits, Culture Cells, Devices, DNA, DNA Templates, Elisa Kits, Equipments, Exosomes, Gels, Isotypes, Medium & Serums, NATtrol, Particles, PCR, Pcr Kits, Peptides, Reagents, Recombinant Proteins, Ria Kits, RNA, Test Kits, Vector & Virus, Western Blot | Jonathan -

Cell adhesion to neighboring cells is a elementary organic course of in multicellular organisms that’s required for tissue morphogenesis. A decent coordination between cell-cell adhesion, signaling, and gene expression is a attribute function of regular tissues. Modifications, and infrequently disruption of this coordination, are widespread throughout invasive and metastatic most cancers improvement. The Wnt/β-catenin signaling pathway is

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“Wnt/β-Catenin Target Genes in Colon Cancer Metastasis: The Special Case of L1CAM”

Single-cell network biology for resolving cellular heterogeneity in human diseases

at 5:23 pm | Antibodies, Assay Kits, Biology Cells, cDNA, Clia Kits, Culture Cells, Devices, DNA, DNA Templates, Elisa Kits, Enzymes, Exosomes, Gels, Isotypes, Medium & Serums, NATtrol, Particles, PCR, Pcr Kits, Peptides, Reagents, Recombinant Proteins, Ria Kits, RNA, Test Kits, Vector & Virus | Jonathan -

Understanding mobile heterogeneity is the holy grail of biology and drugs. Cells harboring an identical genomes present all kinds of behaviors in multicellular organisms. Genetic circuits underlying cell-type identities will facilitate the understanding of the regulatory applications for differentiation and upkeep of distinct mobile states. Such a cell-type-specific gene community may be inferred from coregulatory patterns throughout

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“Single-cell network biology for resolving cellular heterogeneity in human diseases”

To Kill But Not Be Killed: Controlling the Activity of Mammalian Pore-Forming Proteins

at 5:23 pm | Antibodies, Assay Kits, Biology Cells, cDNA, Culture Cells, Devices, DNA, DNA Templates, Elisa Kits, Enzymes, Equipments, Exosomes, Isotypes, Medium & Serums, NATtrol, Panel, Particles, Pcr Kits, Peptides, Reagents, Recombinant Proteins, Ria Kits, RNA, Test Kits, Vector & Virus, Western Blot | Jonathan -

Pore-forming proteins (PFPs) are current in all domains of life, and play an essential function in host-pathogen warfare and within the elimination of cancers. They are often employed to ship particular effectors throughout membranes, to disrupt membrane integrity interfering with cell homeostasis, and to lyse membranes both destroying intracellular organelles or whole cells. Contemplating the

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“To Kill But Not Be Killed: Controlling the Activity of Mammalian Pore-Forming Proteins”

The genetic basis for the evolution of soma: mechanistic evidence for the co-option of a stress-induced gene into a developmental master regulator

at 5:23 pm | Antibodies, Assay Kits, Biology Cells, cDNA, Clia Kits, Culture Cells, Devices, DNA Templates, Elisa Kits, Enzymes, Equipments, Exosomes, Gels, Isotypes, Medium & Serums, Panel, Particles, PCR, Pcr Kits, Peptides, Reagents, Recombinant Proteins, Ria Kits, RNA, Test Kits, Vector & Virus, Western Blot | Jonathan -

In multicellular organisms with specialised cells, probably the most vital distinction amongst cell varieties is between reproductive (germ) cells and non-reproductive/somatic cells (soma). Though soma contributed to the marked improve in complexity of many multicellular lineages, little is understood about its evolutionary origins. Now we have beforehand steered that the evolution of genes answerable for the differentiation of somatic cells

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“The genetic basis for the evolution of soma: mechanistic evidence for the co-option of a stress-induced gene into a developmental master regulator”